Publications

2016-2017

Avery, J. and Dalton, S. (2016). Methods for Derivation of Multipotent Neural Crest Cells Derived from Human Pluripotent Stem Cells. Methods Mol Biol. 1341, 197-208.

Chappell, J., Boward, B. and Dalton, S. (2016). Expanding the Utility of FUCCI Reporters Using FACS-Based Omics Analysis. Methods Mol Biol. 1341, 101-110.

Boward, B., Wu, T. and Dalton, S. (2016). Control of cell fate through cell cycle and pluripotency networks. Stem Cells 34, 1427-1436.

Zhang, W., Li, Y., Kulik, M., Tiedemann, R.L., Robertson, K.D., Dalton, S. and Zhao, S. (2016). Nucleosome positioning changes during human embryonic stem cell differentiation. Epigenetics 11, 426-437.

Berger, R.P., Sun, Y.H., Kulik, M., Lee, J.K., Nairn, A.V., Moremen, K.W. and Pierce, M. and Dalton S.(2016). ST8SIA4 Dependent Polysialylation is Part of a Developmental program Required for Germ Layer Formation from Human Pluripotent Stem Cells. Stem Cells 34, 1742-1752.

Soufi, A. and Dalton, S. (2016). Cycling through developmental decisions: how cell cycle dynamics control pluripotency, differentiation and reprogramming. Development 143, 4301-4311.

Berger, R.P., Dookwah, M., Steet, R. and Dalton S. (2016). Glycosylation and stem cells: Regulatory roles and application of iPSCs in the study of glycosylation-related disorders. Bioessays 38, 1255-1265.

Cliff, T.S. and Dalton, S. (2017). Metabolic switching and cell fate decisions: implications for pluripotency, reprogramming and development. Curr Opin Genet Dev. 46, 44-49.

2015

Garitaonandia, I., Amir, H., Boscolo, F.S., Wambua, G.K., Schultheisz, H.L., Sabatini, K., Morey, R., Waltz, S., Wang, Y.C., Tran, H., Leonardo, T.R., Nazor, K., Slavin, I., Lynch, C., Li, Y., Coleman, R., Gallego Romero, I., Altun, G., Reynolds, D., Dalton, S., Parast, M., Loring, J.F. and Laurent, L.C. (2015). Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions. PLoS One. 10(2):e0118307.

Singh, A.M., Sun, Y., Li L., Zhang, W., Zhao, S., Qin, Z. and Dalton, S. (2015). Cell Cycle Control of Bivalent Epigenetic Domains Regulates the Exit from Pluripotency. Stem Cell Reports 5, 323-336.

Xiao, T., Liu, L., Li, H, Sun, Y., Luo, H., Li, T., Wang, S., Dalton, S., Zhao, R.C. Chen, R. (2015). Long Noncoding RNA ADINR regulates adipogenesis by transcriptionally activating C/EBPα. Stem Cell Reports. S2213-6711.

Singh, A.M., Trost, R., Boward, B. and Dalton S. (2015). Utilizing FUCCI reporters to understand pluripotent stem cell biology. Methods S1046-2023.

Rivera-Mulia, J.C., Buckley, Q., Sasaki, T., Zimmerman, J., Didier, R.A., Nazor, K., Loring, J.F., Lian, Z., Weissman, S., Robins, A.J., Schulz, T.C., Menendez, L., Kulik, M.J., Dalton, S., Gabr, H., Kahveci, T. and Gilbert, D.M. (2015). Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells. Genome Res. 25, 1091-103.

Ryall, J.G., Cliff, T., Dalton, S. and Sartorelli, V. (2015). Metabolic Reprogramming of Stem Cell Epigenetics. Cell Stem Cell 17, 651-662.

Dalton, S. (2015). Linking the Cell Cycle to Cell Fate Decisions. Trends Cell Biol. 25, 592-600.

2011-2014

Ryba, T., Hiratani, I., Battaglia, D., Kulik, M., Zhang, J., Dalton, S. and Gilbert, D.M. (2011). Replication Timing: A Fingerprint for Cell Identity and Pluripotency. PLoS Comp Biol. 7, e1002225.

Dalton, S. (2011). Research spotlight. ‘Trans-differentiation of cells’. Regenerative Med. 6, 8-10.

Smith, K.N., Lim, J.M., Wells, L. and Dalton, S. (2011). Myc orchestrates a regulatory network for the establishment and maintenance of pluripotency. Cell Cycle 10, 592-597.

Menendez, L., Yatskievych, Antin, P.A. and Dalton, S. (2011). Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest-like cells. Proc Natl Acad Sci. USA. 108, 19240-19245.

Bechard, M., Trost, R., Singh, A. and Dalton, S. (2012). Frat is a PI3K/Akt-regulated determinant of GSK3b subcellular localization in pluripotent cells. Mol Cell Biol. 32, 288- 296.

Singh, A.M., Reynolds, D., Cliff, T., Ohtsuka, S., Mathyses, A., Sun, Y., Menendez, L., Kulik, M. and Dalton, S. (2012). Signaling network cross-talk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation. Cell Stem Cell 10, 312-326.

Vickers, D.A., Kulik, M., Hincapie, M., Hancock, W.S., Dalton, S. and Murthy, S. (2012). Lectin-functionalized microchannels for characterizing pluripotent cells and early differentiation. Biomicrofluidics 6, 24122-241220.

Wu, X., Robotham, J.M., Lee, E., Dalton, S., Kneteman, N.M., Gilbert, D.M. and Tang, H. (2012). Productive hepatitis C virus infection of stem cell-derived hepatocytes reveals a critical transition to viral permissiveness during differentiation. PLoS Pathog. 8, e1002617.

Kraushaar, D.C., Rai, S., Condac, E., Nairn, A., Zhang, S., Yamaguchi, Y., Moremen, K., Dalton, S. and Wang, L. (2012). Heparin sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells. J Biol Chem. 287, 22691-22700.

Singh, A.M., Bechard, M., Smith, K. and Dalton, S. (2012). Reconciling the different

roles of Gsk3β in ‘naïve’ and ‘primed’ pluripotent stem cells. Cell Cycle. 11:2991-2996.

Jin, B., Ernst, J., Tiedemann, R.L., Xu, H., Sureshchandra, S., Kellis, M., Dalton, S., Liu, C., Choi, J.H. and Robertson, K.D. (2012). Linking DNA methyltransferases to epigenetic marks and nucleosome structure genome-wide in human tumor cells. Cell Rep. 2, 1411-1424.

Liu, S., Im, H., Bairoch, A., Cristofanilli, M., Chen, R., Deutsch, E.W., Dalton, S., Fenyo, D., Fanayan, S., Gates, C., Gaudet, P., Hincapie, M., Hanash, S., Kim, H., Jeong, S.K., Lundberg, E., Mias, G., Menon, R., Mu, Z., Nice, E., Paik, Y.K., Uhlen, M., Wells, L., Wu, S.L., Yan, F., Zhang, F., Zhang, Y., Snyder, M., Omenn, G.S., Beavis, R.C. and Hancock, W.S. (2013). A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17. J Proteome Res. 12, 45- 57.

Kraushaar, D.C., Dalton, S. and Wang, L. (2013). Heparan sulfate: a key regulator of embryonic stem cell fate. Biol Chem. 394, 741-751.

Menendez, L., Kulik, M.J., Page, A.T., Park, S.S., Lauderdale, J.D., Cunningham, M.L. and Dalton, S. (2013). Directed differentiation of human pluripotent cells to neural crest stem cells. Nature Protocols 8, 203-212.

Chappell, J., Sun, Y., Singh, A. and Dalton S. (2013). MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7. Genes Dev. 27, 725-733.

Phillips-Cremins, J.E., Sauria, M.E., Sanyal, A., Gerasimova, T.I., Lajoie, B.R., Bell, J.S., Ong, C.T., Hookway, T.A., Guo, C., Sun, Y., Bland, M.J., Wagstaff, W., Dalton, S., McDevitt, T.C., Sen, R., Dekker, J., Taylor, J. and Corces, V.G. (2013). Architectural protein subclasses shape 3D organization of genomes during lineage commitment. Cell 153, 1281-1295.

Singh, A.M., Chappell, J., Trost, R., Lin, L., Wang, T., Tang, J., Wu, H., Zhao, S., Jin, P. and Dalton, S. (2013). Cell cycle control of developmentally regulated transcription factors accounts for heterogeneity in human pluripotent cells. Stem Cell Reports 5, 532- 544.

Gasimli, L., Hickey, A.M., Yang, B., Li, G., Dela Rosa, M., Nairn, A.V., Kulik, M.J., Dordick, J.S., Moremen, K.W., Dalton, S. and Linhardt, R.J. 2014. Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards

mesoderm and endoderm lineages. Biochim Biophys Acta 1840,1993-2003.

Tang, J., Li, Y., Lyon, K., Camps, J., Dalton, S., Ried, T. and Zhao, S. (2014). Cancer driver-passenger distinction via sporadic human and dog cancer comparison: a proof-of- principle study with colorectal cancer. Oncogene 33, 814-822.

Dalton, S. (2013). Signaling networks in human pluripotent stem cells. Curr Opin Cell Biol. 25, 241-246.

Dalton, S. (2013). G1 compartmentalization and cell fate coordination. Cell 155, 13-14.

Li, Y., Xu, J., Xiong, H., Ma, Z., Wang, Z., Kipreos, E.T., Dalton, S. and Zhao S. (2014). Cancer driver candidate genes AVL9, DENND5A and NUPL1 contribute to MDCK cystogenesis. Oncoscience 1, 854-865.

Liu, D., Xiong, H., Ellis, A.E., Northrup, N.C., Rodriguez, C.O. Jr, O’Regan, R.M., Dalton, S. and Zhao, S. (2014). Molecular homology and difference between spontaneous canine mammary cancer and human breast cancer. Cancer Res. 74, 5045-5056.